Synergistic antimicrobial combination with cumin extract and some antibiotics on Staphylococcus aureus from chickens

Document Type : Original Article

Authors

1 Department of Bacteriology, Immunology and Mycology Fac. Vet. Med Benha University, Egypt

2 Department of Microbiology Fac. Vet. Med Zagazig University, Egypt

3 Department of Microbiology Animal Health Research institute Egypt

Abstract

In the present study, antimicrobial activity of methanol Cuminum cyminum extract (50mg/ml) in combination with some
antibiotics were investigated against Staphylococcus aureus isolates. The antimicrobial sensitivity pattern of these
isolates in vitro was done and the intermediate isolates were checked for combination with methanol Cuminum cyminum
extract after detecting their antimicrobial activities against these isolates by both disc diffusion test and MIC and the
results showed that the antimicrobial activities of rifampicin, enrofloxacin, doxycycline, gentamicin, and erythromycin
were enhanced in combination with methanol Cuminum cyminum extract the obtained data showed that enhancement by
both disc diffusion test and MIC for methanol Cuminum cyminum extract and each of mentioned antibiotics in decimal
assay of additivity ratio (0.5 for rifampicin and erythromycin and 0.5 for extract ,0.7 for enrofloxacin, and 0.3 for
extract,0.6 for doxycycline, gentamicin and 0.4 for extract) against S.aureus isolates

Keywords

Files

Share

How to cite

Statistics