BIOCHEMICAL EFFECT OF TOXOPLASMA INFESTATION ON IMMUNITY AND INFLAMMATORY MARKERS IN ABORTED WOMENS

Document Type : Original Article

Authors

Department of Biochemistry, Fac. of Vet. Med., Benha Univ., Egypt

Abstract

This study was performed to investigate the effect of toxoplasmosis on several biochemical parameters in
aborted women (aborted due to toxoplasma) 43 women were classified into four groups. The first group
contains 10 women with full term of pregnancy and normal delivers kept as control group. The second group
composed of 16 women aborted one time the third group contain 10 women aborted for two time. Fourth
group contain 7 women aborted for three time. Blood sample were collected from all women. The obtained
result reveled that a significant increase of serum toxoplasma IgG, IgM and cortisol, on aborted groups (G2,
G3 and G4) compared with control group (G1). While, there was none significance difference in cancer
antigen 125 (CA125) in serum compared with control group. Also, Results showed a significant increase of
immunoglobulin IgG, IgE, IgA, IL2 and IL6 and on aborted groups (G2, G3 and G4) compared with control
group (G1). While, there was no significant difference of IgM between in group G4 compared with control
group (G1).

Keywords