Antitumor Effect of Mesenchymal Stem Cells from Murine in Breast Cancer in Female Rats

Document Type : Original Article

Authors

1 of Clinical Biochemistry, Faculty of Veterinary Medicine, Benha University

2 Department of Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, Egypt

3 Assistant Professor Microbiology department, National center for Radiation Research and Technology ,Atomic Energy Authority, Cairo, Egypt,

4 Biochemistry department, Faculty of Veterinary Medicine, Benha University

Abstract

The aim of this study was to evaluate the effect of mesenchymal stem cells as a treatment against breast cancer via modulation TGF-β.
Mesenchymal stem cells (MSCs) are recruited to the stroma of cancers. They interact with cancer cells to promote invasion and metastasis or to suppress tumor growth. The unique
tumor-homing capacity of MSCs makes them a promising vehicle to deliver various anticancer agents.

Main Subjects

Benha Veterinary Medical Journal
Volume 35, Issue 1
September 2018
Pages 369-374

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