The potential anticancer effect of [Cadmium-N Acetyl cysteine] as novel drug therapy for mammary cancer induced by Di Methyl Benzene Anthanthrene in rats

Document Type : Original Article

Authors

1 Biochemistry Department, Faculty of Vet. Med. Moshtohor, Benha University, Egypt.

2 Radiation Biology Department, National Center for Radiation Research and Technology (NCRRT), Atomic Energy Authority, Egypt.

3 Professor of Inorganic Chemistry, Faculty of Science Cairo University.

Abstract

The discovery of Cisplatin triggered the development of novel drugs containing other metals. Extremely diverse structural Chemistry and interaction of metal with ligand resulted in exploration of novel metal complexes with drug potential. The present work carried on 80 female rats which divided into four groups, after 12 weeks the mammary tumor appeared the possible anti-cancer effect of (Cadmium-N Acetyl Cysteine) which has been synthesized and study its effect on (Cd44, Cyclin D1, p21, caspase3, caspase 9 and cell cycle) were investigated on bearing solid mammary tumor induced by DMBA in rats

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Benha Veterinary Medical Journal
Volume 34, Issue 3
August 2018
Pages 232-245

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