The impact of β glucan on the Immune Response of Broiler Chickens Vaccinated with NDV and AI H9V Vaccines

Abd E LTawab, Ashraf Awad; Elnaggar, Omnia Mohammed Ahmed Ali; Elsissi, Ashgan Fahmi

doi:10.21608/bvmj.2019.13775.1021

The impact of β glucan on the Immune Response of Broiler Chickens Vaccinated with NDV and AI H9V Vaccines

Document Type : Original Article

Authors

¹ Department of Bacteriology, Immunology and Mycology Faculty of Veterinary Medicine .,Benha University, Egypt.

² Bacteriology, Immunology and Mycology dep. Fac. med. vet. Benha Universit

³ Department of Immunology, Animal Health Research Institute, Dokki, Giza, Egypt.

10.21608/bvmj.2019.13775.1021

Abstract

To evaluate the effects of β glucan on innate and adaptive immune responses of broilers chickens vaccinated for routine vaccination with Newcastle disease virus (NDV) and Avian Influenza H9N2 (AIV) vaccines. A total of 180 chicks of one-day old Hubbard local breedThey were divided into three groups (sixty chicks for each group). The first group fed with normal broiler diet without any additives and served as control group, while the other two groups consumed diets contained (200mg , 400mg pure β glucan /kg diet respectively for twenty four days of the experimental period. We noticed that, the administration of β glucan to broiler chickens early in life increased significantly (p<0.05) the nitric oxide levels, lysozyme activity, phagocytic activity, and phagocytic index , in addition improved the oxidative state by decreasing malondialdehyde (MDA) and increasing glutathione (GSH) and. High concentration of β glucan improves immune response to NDV and AIV vaccines.

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