Mohammed, M., Abo zaid, O., Moawed, F., Elshawi, O. (2021). Calories restriction modulates the enzymatic antioxidant status in D-galactose induced aging in male rats. Benha Veterinary Medical Journal, 40(2), 96-99. doi: 10.21608/bvmj.2021.67211.1359
Mohammed Abdel-Fattah Mohammed; omayma ragab Abo zaid; Fatma S.M Moawed; Omama El emam Elshawi. "Calories restriction modulates the enzymatic antioxidant status in D-galactose induced aging in male rats". Benha Veterinary Medical Journal, 40, 2, 2021, 96-99. doi: 10.21608/bvmj.2021.67211.1359
Mohammed, M., Abo zaid, O., Moawed, F., Elshawi, O. (2021). 'Calories restriction modulates the enzymatic antioxidant status in D-galactose induced aging in male rats', Benha Veterinary Medical Journal, 40(2), pp. 96-99. doi: 10.21608/bvmj.2021.67211.1359
Mohammed, M., Abo zaid, O., Moawed, F., Elshawi, O. Calories restriction modulates the enzymatic antioxidant status in D-galactose induced aging in male rats. Benha Veterinary Medical Journal, 2021; 40(2): 96-99. doi: 10.21608/bvmj.2021.67211.1359
Calories restriction modulates the enzymatic antioxidant status in D-galactose induced aging in male rats
1biochemistry department faculty of veterinary Banha university
2Biochemistry veterinary medicine Banha university
3Health radiation research, National Center for Radiation Research and Technology, Atomic Energy Authority, Cairo, Egypt
4atomic energy authority
Abstract
In postindustrial and modern societies, overeating and high calories consumption has emerged as new challenge in community health. Large effort is now being devoted to detect and evaluate the pathophysiologic consequences of aging and aging accompanying diseases. Several lines of evidence propose that caloric intake influences the speed of aging and the onset of linked diseases in animals and, possibly, humans. These are the clues of decreasing calories intake in this study to evaluate the effect on aging and to detect weather there are ways to control it. Thirty adult male albino rats were used in this work. ten rats as the control group, D-galactose was injected intraperitoneally to induce aging, then rats were sub divided into equal two groups, one group subjected to calories reduction while-the-other-took-normal-diet-.Catalase,-glutathione-and-MDA-were carried out to test the oxidative effect of D-galactose and possible protective effect of treatments. D-galactose induced impaired oxidative functions. Calories reduction improved D-galactose induced deterioration to a great extent as evidenced biochemically.
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